2-HYDROXY-2-METHYLBUTYRIC ACID
2-Hydroxy-2-Methylbutyric Acid
CAS: 3739-30-8
Molecular Formula: C5H10O3
2-HYDROXY-2-METHYLBUTYRIC ACID - Names and Identifiers
| Name | 2-Hydroxy-2-Methylbutyric Acid |
| Synonyms | 2-hydroxy-2-methyl-butanoicaci 2-Hydroxy-2-Methylbutyric Acid 2-HYDROXY-2-METHYLBUTYRIC ACID 2-Ethyl-2-hydroxypropionic acid 2-HYDROXY-2-METHYLBUTANOIC ACID 2-hydroxy-2-methylbutanoic acid 2-HYDROXY-2-METHYL-N-BUTYRIC ACID 2-Hydroxy-2-methyl-n-butyric acid Butanoic acid, 2-hydroxy-2-methyl- |
| CAS | 3739-30-8 |
| EINECS | 223-120-7 |
| InChI | InChI=1/C5H10O3/c1-3-5(2,8)4(6)7/h8H,3H2,1-2H3,(H,6,7) |
2-HYDROXY-2-METHYLBUTYRIC ACID - Physico-chemical Properties
| Molecular Formula | C5H10O3 |
| Molar Mass | 118.13 |
| Density | 1.144±0.06 g/cm3(Predicted) |
| Melting Point | 73-75 °C (lit.) |
| Boling Point | 109 °C / 9mmHg |
| Flash Point | 111.8°C |
| Water Solubility | within almost transparency |
| Vapor Presure | 0.00793mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| pKa | pK1:3.991 (18°C) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.459 |
| MDL | MFCD00004476 |
2-HYDROXY-2-METHYLBUTYRIC ACID - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
2-HYDROXY-2-METHYLBUTYRIC ACID - Reference Information
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| overview | currently HMB is mainly produced by chemical methods, with low yield, high cost, many by-products and serious environmental pollution. In 1981, the Hasegawa reported that β-methylbutyric acid produced HMB. In 1997, the fermentation process of transforming MBA to produce HMB was preliminarily explored. Some work was done in the improvement of culture medium and the optimization of culture conditions, which improved the ability of the strain to transform MBA to produce HMB. |
| Uses | The calcium salt of β-hydroxy-β-methylbutyric acid (HMB) can be used as a functional feed additive to promote animal growth, reduce fat, increase lean meat, and ensure animal health; it can also be used as a health product for athletes to prevent muscle damage and muscle protein breakage during endurance training; it can also be used as an effective ingredient in weight loss foods, it has broad market prospects. |
| Biological activity | 2-Hydroxy-2-methylbutyric acid is an abnormal metabolite found in the urine of patients, usually found in the urine of patients with hydroxyglutaric aciduria and maple diabetes. Acid is also a secondary metabolite found in urine after exposure to gasoline additive TAME. |
Last Update：2024-04-09 02:00:08
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View History
2-HYDROXY-2-METHYLBUTYRIC ACID
1-O-Acetylbritannilatone
Phenol, 2-fluoro-6-nitro-
2-氯-5-[(甲基硫烷基)甲基]吡啶
2-(4-氟-3-甲基苯基)乙酸
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2-羟基-3-萘甲酰基-1-萘胺
PYRIDINIUM N-PROPYL HYDROXY SULFOBETAINE
Α-氯甘油,3-氯丙二醇
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1-O-Acetylbritannilatone
Phenol, 2-fluoro-6-nitro-
2-氯-5-[(甲基硫烷基)甲基]吡啶
2-(4-氟-3-甲基苯基)乙酸
1-苄氧基羰基六氢哒嗪-3-羧酸
2-羟基-3-萘甲酰基-1-萘胺
PYRIDINIUM N-PROPYL HYDROXY SULFOBETAINE
Α-氯甘油,3-氯丙二醇
中性红染色法特殊细胞染色试剂盒